> For the complete documentation index, see [llms.txt](https://help.bioinsight.illumina.com/llms.txt). Markdown versions of documentation pages are available by appending `.md` to page URLs; this page is available as [Markdown](https://help.bioinsight.illumina.com/ora/product-guides/dragen-ora-decompression.md).

# DRAGEN ORA Decompression v2.7

{% hint style="warning" %} <mark style="color:orange;">**Warning**</mark>\ <mark style="color:orange;">**Do not use this documentation for decompression on the DRAGEN Server. The DRAGEN Server has its own integrated DRAGEN ORA Decompression component**</mark><mark style="color:orange;">.</mark>
{% endhint %}

DRAGEN ORA Decompression Software decompresses fastq.ora files into fastq.gz files. Fastq.ora files are generated using lossless compression technology as part of DRAGEN. Orad is the executable file that runs the DRAGEN ORA Decompression Software, which is a standalone piece of software.

With DRAGEN v4.3, compression of FASTQ files derived from supported non-human species and from human bisulfite data (methylated DNA application) is available. DRAGEN ORA decompression v2.7 allows for the decompression of FASTQ.ORA compressed with all supported references. Refer to the [References Installation](/ora/product-guides/dragen-ora-decompression/references-installation.md) and [Supported References](/ora/reference/supported-references.md) sections.

The DRAGEN ORA Decompression Software is available for the following operating systems in three separated executable:

* Linux
* Mac
* Windows

Decompression of FASTQ.ORA stored on local storage is supported on Linux, Mac, and Windows. Decompression of FASTQ.ORA stored on AWS S3 is only supported on Linux.

Decompression of FASTQ.ORA stored on Azure Blob storage is only supported on Linux.

When FASTQ.ORA is located on AWS S3 or Azure Blob storage, the decompression occurs on a streaming mode: the FASTQ.ORA file does not need to be fully transferred before decompression can start.


---

# Agent Instructions
This documentation is published with GitBook. GitBook is the documentation platform designed so that both humans and AI agents can read, navigate, and reason over technical content effectively. Learn more at gitbook.com.

## Querying This Documentation
If you need additional information that is not directly available in this page, you can query the documentation by asking a question.

Perform an HTTP GET request on the following URL with the `ask` and `goal` query parameters:

```
GET https://help.bioinsight.illumina.com/ora/product-guides/dragen-ora-decompression.md?ask=<question>&goal=<user_goal>
```

`ask` is the immediate question: it should be specific, self-contained, and written in natural language.
`goal` is what the user is ultimately trying to achieve, the reason they need the answer. Sharing it helps GitBook give you a better, more relevant answer. A goal is most helpful when it describes the outcome the user wants rather than restating the question. For example, with `ask=how do I create an API token`, a goal like `automate deployments from our CI pipeline` lets GitBook tailor the answer to that use case.

The response will contain a direct answer to the question and relevant excerpts and sources from the documentation.

Use this mechanism when the answer is not explicitly present in the current page, you need clarification or additional context, or you want to retrieve related documentation sections.