> For the complete documentation index, see [llms.txt](https://help.bioinsight.illumina.com/llms.txt). Markdown versions of documentation pages are available by appending `.md` to page URLs; this page is available as [Markdown](https://help.bioinsight.illumina.com/emedgene/emedgene-curate-manual/curate_variants/curate_variant_page/variant-information-card.md).

# Variant information card

## Card contents

The **Variant information card** on the [**Curate Variant page**](/emedgene/emedgene-curate-manual/curate_variants/curate_variant_page.md) shows key variant details.

### Small variants

<div align="left"><figure><img src="https://1131024994-files.gitbook.io/~/files/v0/b/gitbook-x-prod.appspot.com/o/spaces%2FGCW0DnLlE7QjoZPNmKIi%2Fuploads%2Fgit-blob-b6f4ad48cb7aa4ea2f46b37238e45d41650d0587%2Fimage%20(161)%20(2).png?alt=media" alt="" width="493"><figcaption><p><strong>Variant information card</strong> for a small variant.</p></figcaption></figure></div>

For small variants, including those in mtDNA, the **Variant information card** displays:

* Variant type: `SNV`, `small ins`, or `small del`
* [Main variant effect](/emedgene/emedgene-analyze-manual/tertiary-analysis-pipeline/how_does_emedgene_calculate_variant_effect_and_severity.md)
* Affected gene
* HGVS variant description

### CNVs

<div align="left"><figure><img src="https://1131024994-files.gitbook.io/~/files/v0/b/gitbook-x-prod.appspot.com/o/spaces%2FGCW0DnLlE7QjoZPNmKIi%2Fuploads%2Fgit-blob-d6a64b593980271b23545794b82c85103e1e1ac6%2Fimage%20(161).png?alt=media" alt="" width="491"><figcaption><p><strong>Variant information card</strong> for a copy number variant.</p></figcaption></figure></div>

For copy number variants, the **Variant information card** displays:

* Variant type: `DEL` or `DUP`
* Variant length
* List of affected genes

***

## How to update a reference transcript for a small variant

<figure><img src="https://1131024994-files.gitbook.io/~/files/v0/b/gitbook-x-prod.appspot.com/o/spaces%2FGCW0DnLlE7QjoZPNmKIi%2Fuploads%2Fgit-blob-16e12641a8a4fca77c5fc20cda67d0c45d9dea0f%2Flegacy_Curate_variant_page_Variant_information_change_transcript.gif?alt=media" alt=""><figcaption><p>Updating the reference transcript for a small variant.</p></figcaption></figure>

You can select or change a reference transcript for a small variant from the dropdown menu.

{% stepper %}
{% step %}
Open the reference transcript dropdown in the **Variant information card**.
{% endstep %}

{% step %}
Select the reference transcript you want to apply.
{% endstep %}
{% endstepper %}

**Result:** The affected gene, main variant effect, and HGVS variant description are updated in the **Variant information card** and in the page header.


---

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