> For the complete documentation index, see [llms.txt](https://help.bioinsight.illumina.com/llms.txt). Markdown versions of documentation pages are available by appending `.md` to page URLs; this page is available as [Markdown](https://help.bioinsight.illumina.com/emedgene/emedgene-curate-manual/curate_variants/curate_variant_page/top-bar.md).
# Header
## Header contents
The header of the [**Curate Variant page**](/emedgene/emedgene-curate-manual/curate_variants/curate_variant_page.md) shows the key identifying details of the variant, pathogenicity classification, and curation status (v100.41+).
### Small variants
Header of the Curate Variant page for a small variant.
For small variants, including mtDNA variants, the header highlights:
* Clickable gene symbol linked to the gene page in [**Curate Genes**](/emedgene/emedgene-curate-manual/curate_genes_2_28.md)
* Variant type: `SNV`, `small ins`, or `small del`
* Genomic position and nucleotide change
* HGVS variant description
* [Main variant effect](/emedgene/emedgene-analyze-manual/tertiary-analysis-pipeline/how_does_emedgene_calculate_variant_effect_and_severity.md)
* Pathogenicity classification
* Curation status (v100.41+)
### CNVs
Header of the Curate Variant page for a copy number variant.
For copy number variants, the header highlights:
* For each involved gene, a clickable gene symbol linked to the gene page in [**Curate Genes**](/emedgene/emedgene-curate-manual/curate_genes_2_28.md)
* Variant type: `DEL` or `DUP`
* Genomic range and variant length
* Pathogenicity classification
* Curation status (v100.41+)
***
## How to update curated variant pathogenicity
{% stepper %}
{% step %}
In the header of the **Curate Variant page**, select **Pathogenicity**.
{% endstep %}
{% step %}
From the dropdown, select the classification you want to assign to the variant.
{% endstep %}
{% endstepper %}
**Result:** The pathogenicity classification is updated for the variant and used in future case annotations.
***
## How to update the variant curation status (v100.41+)
Use the curation status dropdown in the header to set the review state of the variant's curated data.
{% hint style="info" %}
For a network-only variant, the curation status shows **NA** and cannot be changed.
{% endhint %}
**Prerequisite:** You need [permissions](/emedgene/emedgene-analyze-manual/settings/user_roles/iam-scopes-emedgene-roles.md) to change the curation status.
{% stepper %}
{% step %}
In the header of the **Curate Variant page**, select the curation status dropdown.
{% endstep %}
{% step %}
From the dropdown, select **Draft**, **Pending review**, **Approved**, **Reclassification needed**, or **Artifact**.
{% endstep %}
{% endstepper %}
**Result:**
* The curation status is updated for the variant.
* The change is recorded in the [**Activities panel**](/emedgene/emedgene-curate-manual/curate_variants/curate_variant_page/activities-panel.md).
---
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