> For the complete documentation index, see [llms.txt](https://help.bioinsight.illumina.com/llms.txt). Markdown versions of documentation pages are available by appending `.md` to page URLs; this page is available as [Markdown](https://help.bioinsight.illumina.com/emedgene/emedgene-analyze-manual/variant_page/quality_section/allele-distribution.md).

# Allele distribution

Review how sequencing reads support reference and alternate alleles.

The **Allele distribution card** of the **Quality tab** shows how sequencing reads support the reference and alternate allele.

It is available for SNVs, MNVs, indels (both nuclear and mitochondrial), and STRs.

## SNVs, MNVs, and indels

{% hint style="info" %}
The MNV variant type is supported from version 100.39.0.
{% endhint %}

{% columns %}
{% column width="41.66666666666667%" %}

<figure><img src="https://1131024994-files.gitbook.io/~/files/v0/b/gitbook-x-prod.appspot.com/o/spaces%2FGCW0DnLlE7QjoZPNmKIi%2Fuploads%2Fgit-blob-95692da52defe222e98b9a6a211510f2bba4da9a%2Fallele%20distribution%20small%20variants.gif?alt=media" alt=""><figcaption></figcaption></figure>
{% endcolumn %}

{% column width="58.33333333333333%" %}
Allele fractions are shown as pie charts, one per sample. This gives you a quick view of variant distribution across alleles.

{% hint style="info" %}
For [MRJD](https://help.dragen.illumina.com/product-guide/dragen-v4.4/dragen-dna-pipeline/small-variant-calling/multi-region-joint-detection)-called variants, the alternate allele percentage shown in the graph comes from the `JAF` field in the DRAGEN MRJD VCF. `JAF` reports the alternate allele fraction across all paralogous regions.
{% endhint %}
{% endcolumn %}
{% endcolumns %}

## STRs

{% columns %}
{% column width="41.66666666666667%" %}

<div align="left"><figure><img src="https://1131024994-files.gitbook.io/~/files/v0/b/gitbook-x-prod.appspot.com/o/spaces%2FGCW0DnLlE7QjoZPNmKIi%2Fuploads%2Fgit-blob-b54cad115f306c851b474d8ddf70a229bc0786a6%2Fimage%20(116).png?alt=media" alt="" width="266"><figcaption></figcaption></figure></div>
{% endcolumn %}

{% column width="58.33333333333333%" %}
For STRs, the allele distribution table shows how sequencing reads support an STR variant. This helps you assess call accuracy.

The columns are `REF` and `ALT`. They represent reference and alternate allele counts.

Rows are grouped into these categories:

* **In Repeat** — Reads aligning within the repeat. Higher values improve confidence.
* **Flanking** — Reads adjacent to the repeat region.
* **Spanning** — Reads covering the entire repeat region.
  {% endcolumn %}
  {% endcolumns %}


---

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