> For the complete documentation index, see [llms.txt](https://help.bioinsight.illumina.com/llms.txt). Markdown versions of documentation pages are available by appending `.md` to page URLs; this page is available as [Markdown](https://help.bioinsight.illumina.com/connected-insights/configure/configuration/du-introduction/du-supported-pipelines.md). # Supported Pipelines > **Note:** When a new BioInsight Platform Core pipeline subversion is released your existing configurations will need to be refreshed to support them. Under the Data Upload section of the configuration, edit the relevant configuration (no additional actions are necessary) and save the configuration. Connected Insights directly supports the following pipelines: | **Pipeline Name and YAML** | **Support (Local Storage / BioInsight Platform Core)** | **Supported BioInsight Platform Core Pipeline Subversions** | | ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ | ------------------------------------------------------ | ----------------------------------------------------------- | | [DRAGEN TruSight Oncology 500 Analysis Software v2.6.2](/connected-insights/configure/configuration/du-introduction/du-supported-pipelines/dragen-trusight-oncology-500-analysis-software-v2.6.2.md) | Local Storage and BioInsight Platform Core | 2.6.2.4 | | [DRAGEN TruSight Oncology 500 Analysis Software v2.6.1 (with HRD)](/connected-insights/configure/configuration/du-introduction/du-supported-pipelines/dragen-trusight-oncology-500-analysis-software-v2.6.1-with-hrd.md) | Local Storage | N/A | | [DRAGEN TruSight Oncology 500 Analysis Software v2.6.1](/connected-insights/configure/configuration/du-introduction/du-supported-pipelines/dragen-trusight-oncology-500-analysis-software-v2.6.1.md) | Local Storage | N/A | | [DRAGEN TruSight Oncology 500 Analysis Software v2.6.0 (with HRD)](/connected-insights/configure/configuration/du-introduction/du-supported-pipelines/dragen-trusight-oncology-500-analysis-software-v2.6.0-with-hrd.md) | Local Storage and BioInsight Platform Core | 2.6.0.2, 2.6.0.8 | | [DRAGEN TruSight Oncology 500 Analysis Software v2.6.0](/connected-insights/configure/configuration/du-introduction/du-supported-pipelines/dragen-trusight-oncology-500-analysis-software-v2.6.0.md) | Local Storage and BioInsight Platform Core | 2.6.0.2, 2.6.0.8 | | [DRAGEN TruSight Oncology 500 Analysis Software v2.5.4 (with HRD)](https://github.com/illumina-swi/ici-docs/tree/main/docs/configure/configuration/du-introduction/du-supported-pipelines/yamls/DRAGEN-TruSight-Oncology-500-Analysis-Software-v2.5.4-with-HRD.md) | Local Storage | N/A | | [DRAGEN TruSight Oncology 500 Analysis Software v2.5.4](https://github.com/illumina-swi/ici-docs/tree/main/docs/configure/configuration/du-introduction/du-supported-pipelines/yamls/DRAGEN-TruSight-Oncology-500-Analysis-Software-v2.5.4.md) | Local Storage | N/A | | [DRAGEN TruSight Oncology 500 Analysis Software v2.5.3 (with HRD)](/connected-insights/configure/configuration/du-introduction/du-supported-pipelines/dragen-trusight-oncology-500-analysis-software-v2.5.3-with-hrd.md) | Local Storage | N/A | | [DRAGEN TruSight Oncology 500 Analysis Software v2.5.3](/connected-insights/configure/configuration/du-introduction/du-supported-pipelines/dragen-trusight-oncology-500-analysis-software-v2.5.3.md) | Local Storage | N/A | | [DRAGEN TruSight Oncology 500 Analysis Software v2.5.2 (with HRD)](/connected-insights/configure/configuration/du-introduction/du-supported-pipelines/dragen-trusight-oncology-500-analysis-software-v2.5.2-with-hrd.md) | Local Storage and BioInsight Platform Core | 2.5.2.1, 2.5.2.6 | | [DRAGEN TruSight Oncology 500 Analysis Software v2.5.2](/connected-insights/configure/configuration/du-introduction/du-supported-pipelines/dragen-trusight-oncology-500-analysis-software-v2.5.2.md) | Local Storage and BioInsight Platform Core | 2.5.2.1, 2.5.2.6 | | [DRAGEN TruSight Oncology 500 Analysis Software v2.1.2 (with HRD)](/connected-insights/configure/configuration/du-introduction/du-supported-pipelines/dragen-trusight-oncology-500-analysis-software-v2.1.2-with-hrd.md) | Local Storage and BioInsight Platform Core | 2.1.2.3 | | [DRAGEN TruSight Oncology 500 Analysis Software v2.1.2](/connected-insights/configure/configuration/du-introduction/du-supported-pipelines/dragen-trusight-oncology-500-analysis-software-v2.1.2.md) | Local Storage and BioInsight Platform Core | 2.1.2.3 | | [DRAGEN TruSight Oncology 500 Analysis Software v2.1.1 (with HRD)](/connected-insights/configure/configuration/du-introduction/du-supported-pipelines/dragen-trusight-oncology-500-analysis-software-v2.1.1-with-hrd.md) | Local Storage | N/A | | [DRAGEN TruSight Oncology 500 Analysis Software v2.1.1](/connected-insights/configure/configuration/du-introduction/du-supported-pipelines/dragen-trusight-oncology-500-analysis-software-v2.1.1.md) | Local Storage | N/A | | [DRAGEN TruSight Oncology 500 ctDNA Analysis Software v2.6.4](/connected-insights/configure/configuration/du-introduction/du-supported-pipelines/dragen-trusight-oncology-500-ctdna-analysis-software-v2.6.4.md) | Local Storage and BioInsight Platform Core | 2.6.4.5 | | [DRAGEN TruSight Oncology 500 ctDNA Analysis Software v2.6.3](/connected-insights/configure/configuration/du-introduction/du-supported-pipelines/dragen-trusight-oncology-500-ctdna-analysis-software-v2.6.3.md) | Local Storage and BioInsight Platform Core | 2.6.3.4 | | [DRAGEN TruSight Oncology 500 ctDNA Analysis Software v2.6.2](/connected-insights/configure/configuration/du-introduction/du-supported-pipelines/dragen-trusight-oncology-500-ctdna-analysis-software-v2.6.2.md) | Local Storage | N/A | | [DRAGEN TruSight Oncology 500 ctDNA Analysis Software v2.6.1](/connected-insights/configure/configuration/du-introduction/du-supported-pipelines/dragen-trusight-oncology-500-ctdna-analysis-software-v2.6.1.md) | Local Storage and BioInsight Platform Core | 2.6.1.4, 2.6.1.8 | | [DRAGEN TruSight Oncology 500 ctDNA Analysis Software v2.6.0](/connected-insights/configure/configuration/du-introduction/du-supported-pipelines/dragen-trusight-oncology-500-ctdna-analysis-software-v2.6.0.md) | Local Storage and BioInsight Platform Core | 2.6.0.22, 2.6.0.25 | | [DRAGEN TruSight Oncology 500 ctDNA Analysis Software v2.5.0](/connected-insights/configure/configuration/du-introduction/du-supported-pipelines/dragen-trusight-oncology-500-ctdna-analysis-software-v2.5.0.md) | Local Storage and BioInsight Platform Core | 2.5.0.24 | | [DRAGEN TruSight Oncology 500 ctDNA Analysis Software v2.1.1](/connected-insights/configure/configuration/du-introduction/du-supported-pipelines/dragen-trusight-oncology-500-ctdna-analysis-software-v2.1.1.md) | Local Storage and BioInsight Platform Core | 2.1.1.3 | | [DRAGEN Solid WGS Tumor Normal v4.4](/connected-insights/configure/configuration/du-introduction/du-supported-pipelines/dragen-solid-wgs-tn-v4.4.md) | Local Storage and BioInsight Platform Core | 4.4.4.53 | | [DRAGEN Heme v4.4](/connected-insights/configure/configuration/du-introduction/du-supported-pipelines/dragen-heme-v4.4.md) | Local Storage and BioInsight Platform Core | 4.4.4.62, 4.4.6.44 | | [DRAGEN Heme v1.0](/connected-insights/configure/configuration/du-introduction/du-supported-pipelines/dragen-heme-v1.0.md) | Local Storage and BioInsight Platform Core | 1.0.0.8 | | [DRAGEN WGS MRD v4.6](/connected-insights/configure/configuration/du-introduction/du-supported-pipelines/dragen-wgs-mrd-v4.6.md) | Local Storage and BioInsight Platform Core | 4.4 | | [DRAGEN WGS MRD v4.4.6](/connected-insights/configure/configuration/du-introduction/du-supported-pipelines/dragen_wgs_mrd-v4.4.6.md) | Local Storage and BioInsight Platform Core | 4.4.6 | | [DRAGEN Amplicon v4.5](/connected-insights/configure/configuration/du-introduction/du-supported-pipelines/dragen-amplicon-v4.5.md) | Local Storage and BioInsight Platform Core | 4.5.4, 4.5.4 BSSH App | | [DRAGEN Amplicon v4.4](/connected-insights/configure/configuration/du-introduction/du-supported-pipelines/dragen-amplicon-v4.4.md) | Local Storage and BioInsight Platform Core | 4.4.4, 4.4.6 | | [DRAGEN Amplicon v4.3](/connected-insights/configure/configuration/du-introduction/du-supported-pipelines/dragen-amplicon-v4.3.md) | Local Storage and BioInsight Platform Core | 4.3.6, 4.3.13 | | [DRAGEN Amplicon v4.2](/connected-insights/configure/configuration/du-introduction/du-supported-pipelines/dragen-amplicon-v4.2.md) | Local Storage and BioInsight Platform Core | 4.2.4 | | [DRAGEN Amplicon v4.1](/connected-insights/configure/configuration/du-introduction/du-supported-pipelines/dragen-amplicon-v4.1.md) | Local Storage | N/A | | [DRAGEN RNA v4.5](/connected-insights/configure/configuration/du-introduction/du-supported-pipelines/dragen-rna-v4.5.md) | Local Storage and BioInsight Platform Core | 4.5.4 | | [DRAGEN RNA v4.4](/connected-insights/configure/configuration/du-introduction/du-supported-pipelines/dragen-rna-v4.4.md) | Local Storage and BioInsight Platform Core | 4.4.4, 4.4.6 | | [DRAGEN RNA v4.3](/connected-insights/configure/configuration/du-introduction/du-supported-pipelines/dragen-rna-v4.3.md) | Local Storage and BioInsight Platform Core | 4.3.6, 4.3.13, 4.3.16, 4.3.17 | | [DRAGEN RNA v4.2](/connected-insights/configure/configuration/du-introduction/du-supported-pipelines/dragen-rna-v4.2.md) | Local Storage and BioInsight Platform Core | 4.2.4 | | [DRAGEN RNA v4.1](/connected-insights/configure/configuration/du-introduction/du-supported-pipelines/dragen-rna-v4.1.md) | Local Storage and BioInsight Platform Core | 4.1.5, 4.1.23 | | [DRAGEN RNA (RNA Pan-Cancer Panel, RNA Fusion Panel, WTS) v4.0.3](/connected-insights/configure/configuration/du-introduction/du-supported-pipelines/dragen-rna-pan-cancer-panel-v4.0.3.md) | Local Storage and BioInsight Platform Core | 4.0.3 | | [DRAGEN Somatic Enrichment and Whole Genome v4.5](/connected-insights/configure/configuration/du-introduction/du-supported-pipelines/dragen-somatic-enrichment-and-whole-genome-v4.5.md) | Local Storage and BioInsight Platform Core | 4.5.4, 4.5.4 v2, 4.5.4 v3 | | [DRAGEN Somatic Enrichment and Whole Genome v4.4.6](/connected-insights/configure/configuration/du-introduction/du-supported-pipelines/dragen-somatic-enrichment-and-whole-genome-v4.4.6.md) | Local Storage and BioInsight Platform Core | 4.4.6, 4.4.6 v2 | | [DRAGEN Somatic Enrichment v4.4](/connected-insights/configure/configuration/du-introduction/du-supported-pipelines/dragen-enrichment-v4.4.md) | Local Storage and BioInsight Platform Core | 4.4.4, 4.4.6 BSSH App, 4.4.6001 BSSH App | | [DRAGEN Somatic Enrichment v4.3](/connected-insights/configure/configuration/du-introduction/du-supported-pipelines/dragen-enrichment-v4.3.md) | Local Storage and BioInsight Platform Core | 4.3.6, 4.3.13, 4.3.16, 4.3.17 | | [DRAGEN Somatic Enrichment v4.2](/connected-insights/configure/configuration/du-introduction/du-supported-pipelines/dragen-enrichment-v4.2.md) | Local Storage and BioInsight Platform Core | 4.2.4 | | [DRAGEN Somatic Enrichment v4.1](/connected-insights/configure/configuration/du-introduction/du-supported-pipelines/dragen-enrichment-v4.1.md) | Local Storage and BioInsight Platform Core | 4.1.5, 4.1.23 | | [DRAGEN for Illumina cfDNA Prep with Enrichment v4.0.3](/connected-insights/configure/configuration/du-introduction/du-supported-pipelines/dragen-for-illumina-cfdna-prep-with-enrichment-v4.0.3.md) | Local Storage and BioInsight Platform Core | 4.0.3 | | [DRAGEN Somatic Whole Genome v4.5](/connected-insights/configure/configuration/du-introduction/du-supported-pipelines/dragen-somatic-whole-genome-v4.5.md) | Local Storage and BioInsight Platform Core | 4.5.4 | | [DRAGEN Somatic Whole Genome v4.4](/connected-insights/configure/configuration/du-introduction/du-supported-pipelines/dragen-somatic-whole-genome-v4.4.md) | Local Storage and BioInsight Platform Core | 4.4.4, 4.4.4003 BSSH App, 4.4.6 BSSH App, 4.4.6001 BSSH App | | [DRAGEN Somatic Whole Genome v4.3](/connected-insights/configure/configuration/du-introduction/du-supported-pipelines/dragen-somatic-whole-genome-v4.3.md) | Local Storage and BioInsight Platform Core | 4.3.6, 4.3.13, 4.3.16 | | [DRAGEN Somatic Whole Genome v4.2](/connected-insights/configure/configuration/du-introduction/du-supported-pipelines/dragen-somatic-whole-genome-v4.2.md) | Local Storage and BioInsight Platform Core | 4.2.4 | | [DRAGEN Somatic Whole Genome v4.1](/connected-insights/configure/configuration/du-introduction/du-supported-pipelines/dragen-somatic-whole-genome-v4.1.md) | Local Storage and BioInsight Platform Core | 4.1.5, 4.1.23 | | [TruSight Tumor 170 Local App v2.0.1](/connected-insights/configure/configuration/du-introduction/du-supported-pipelines/trusight-tumor-170-local-app-v2.0.1.md) | Local Storage | N/A | | [Local Run Manager TruSight Tumor 15 Analysis Module v2.1](/connected-insights/configure/configuration/du-introduction/du-supported-pipelines/local-run-manager-trusight-tumor-15-analysis-module-v2.1.md) | Local Storage | N/A | | [Local Run Manager TruSight Tumor 15 Analysis Module v2.1](/connected-insights/configure/configuration/du-introduction/du-supported-pipelines/local-run-manager-trusight-tumor-15-analysis-module-v2.1.md) | Local Storage | N/A | | [Archer Analysis v7 (VariantPlex and FusionPlex panels)](/connected-insights/configure/configuration/du-introduction/du-supported-pipelines/archer-analysis-v7.md) | Local Storage | N/A | | [Archer VariantPlex Pipeline v7.3](/connected-insights/configure/configuration/du-introduction/du-supported-pipelines/archer-variantplex-pipeline-v7.3.md) | Local Storage | N/A | | [Pillar Biosciences RUO PiVAT Pipeline v2024](/connected-insights/configure/configuration/du-introduction/du-supported-pipelines/pillar-biosciences-ruo-pivat-pipeline-v2024.md) | Local Storage | N/A | For additional information about DRAGEN TruSight Oncology 500 and other DRAGEN Applications refer to: * [DRAGEN TruSight Oncology 500 Software](https://help.tso500software.illumina.com/) * [DRAGEN Secondary Analysis Software](https://help.dragen.illumina.com/) > **Note:** Archer and Pillar pipeline configurations were developed on a small sample of datasets, if any issues arise, please contact customer support. --- # Agent Instructions This documentation is published with GitBook. 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