> For the complete documentation index, see [llms.txt](https://help.bioinsight.illumina.com/llms.txt). Markdown versions of documentation pages are available by appending `.md` to page URLs; this page is available as [Markdown](https://help.bioinsight.illumina.com/connected-insights/configure/configuration/c-custom-actionability-classification.md).

# Actionability Classifications

Connected Insights provides default actionability classifications based on AMP/ASCO/CAP Li et al., 2017. You may use the predefined ESMO ESCAT, Mateo et al., 2018 definitions when selecting and/or creating new assertions by selecting **ESMO ESCAT, Mateo et al., 2018** or you can create your own custom actionability classifications.

The default classifications are configured based on AMP/ASCO/CAP Li et al., 2017, shared with every workgroup, and cannot be updated. See [Illumina-Provided Default Resources](/connected-insights/configure/configuration.md#illumina-provided-default-resources).

Custom actionability classifications can be set up in Configuration. Later, when you create therapeutic, prognostic, and diagnostic assertions, you can specify these classifications.

Create custom actionability classifications as follows.

1. On the top toolbar, select **Configuration**.
2. In the General tab, select **Actionability Classification**. The default actionability classifications are based on AMP/ASCO/CAP Li et al., 2017. If you want to specify your own, select **I want to classify using my own classifications**.
3. Provide a name for the actionability classifications.
4. Select **Add**.
5. Add a classification name (eg, Level 1).
6. \[Optional] Add a description.
7. Choose a color.
8. Select **Save**.
9. Repeat steps 4–8 until you have your classification created.
   * Classifications can be deleted by selecting x on the created classification.
   * Classifications can be edited by selecting the pencil icon on the created classification.
10. Use the drag handles to map your classifications to the AMP/ASCO/CAP Li et al., 2017 guideline on the right side of the window. Place your classifications in order of their significance. After you create assertions, this order is used to prioritize variants and evidence.

    > ❗ Whenever you edit these classifications, it does not modify existing assertions in your knowledge base or reports. When you encounter assertions using older classifications, they can be edited to use the latest classification.


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